C5Y (p.Cys5Tyr) variant of HTR2A (5-hydroxytryptamine receptor 2A)
C5Y (p.Cys5Tyr) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
C5Y (p.Cys5Tyr) variant details
- p.Cys5Tyr
- TOPMed rs1307418905
- gnomAD rs1307418905
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.01
- CADD 17.40
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available