C148S (p.Cys148Ser) variant of HTR2A (5-hydroxytryptamine receptor 2A)
C148S (p.Cys148Ser) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
C148S (p.Cys148Ser) variant details
- p.Cys148Ser
- gnomAD 13-46892560-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.723
- REVEL 0.67
- MetaLR 0.68
- MetaSVM 0.69
- CADD 26.50
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available