A78V (p.Ala78Val) variant of HTR2A (5-hydroxytryptamine receptor 2A)
A78V (p.Ala78Val) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
A78V (p.Ala78Val) variant details
- p.Ala78Val
- ExAC rs773466572
- gnomAD rs773466572
- Missense
- Variant Prioritization Score for Impact Estimate 0.489
- REVEL 0.35
- MetaLR 0.16
- MetaSVM -0.95
- CADD 29.00
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available