A37V (p.Ala37Val) variant of HTR2A (5-hydroxytryptamine receptor 2A)
A37V (p.Ala37Val) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A37V (p.Ala37Val) variant details
- p.Ala37Val
- TOPMed rs1175309453
- gnomAD rs1175309453
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.17
- MetaLR 0.06
- MetaSVM -1.05
- CADD 12.70
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available