A33S (p.Ala33Ser) variant of HSD3B2 (P26439)
A33S (p.Ala33Ser) in HSD3B2 (P26439) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A33S (p.Ala33Ser) variant details
- p.Ala33Ser
- ExAC rs774377636
- gnomAD rs774377636
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.24
- MetaLR 0.50
- MetaSVM -0.41
- CADD 11.00
- PolyPhen-2 0.26
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available