T35S (p.Thr35Ser) variant of HRAS (GTPase HRas)
T35S (p.Thr35Ser) in HRAS (GTPase HRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
T35S (p.Thr35Ser) variant details
- p.Thr35Ser
- Ensembl rs2133994186
- Missense
- Variant Prioritization Score for Impact Estimate 0.662
- REVEL 0.75
- AlphaMissense 0.99
- MetaLR 0.82
- MetaSVM 0.88
- CADD 24.50
- PolyPhen-2 0.91
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available