S39C (p.Ser39Cys) variant of HRAS (GTPase HRas)
S39C (p.Ser39Cys) in HRAS (GTPase HRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
S39C (p.Ser39Cys) variant details
- p.Ser39Cys
- Ensembl rs2133991841
- Missense
- Variant Prioritization Score for Impact Estimate 0.626
- REVEL 0.69
- AlphaMissense 0.81
- MetaLR 0.56
- MetaSVM 0.22
- CADD 25.30
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available