Q22R (p.Gln22Arg) variant of HRAS (GTPase HRas)
Q22R (p.Gln22Arg) in HRAS (GTPase HRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
Q22R (p.Gln22Arg) variant details
- p.Gln22Arg
- TOPMed rs1445047175
- gnomAD rs1445047175
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.41
- AlphaMissense 0.85
- MetaLR 0.21
- MetaSVM -0.73
- CADD 28.00
- PolyPhen-2 0.82
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available