E3G (p.Glu3Gly) variant of HRAS (GTPase HRas)
E3G (p.Glu3Gly) in HRAS (GTPase HRas) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
E3G (p.Glu3Gly) variant details
- p.Glu3Gly
- Ensembl rs2133995205
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.51
- AlphaMissense 0.86
- MetaLR 0.32
- MetaSVM -0.35
- CADD 23.90
- PolyPhen-2 0.19
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available