W7L (p.Trp7Leu) variant of HOGA1 (Q86XE5)
W7L (p.Trp7Leu) in HOGA1 (Q86XE5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
W7L (p.Trp7Leu) variant details
- p.Trp7Leu
- gnomAD 10-97584723-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.25
- ESM-1b 0.00
- AlphaMissense 0.11
- MetaLR 0.63
- MetaSVM 0.17
- CADD 20.80
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available