T66I (p.Thr66Ile) variant of HOGA1 (Q86XE5)
T66I (p.Thr66Ile) in HOGA1 (Q86XE5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
T66I (p.Thr66Ile) variant details
- p.Thr66Ile
- Ensembl rs1564753736
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.21
- ESM-1b 1.00
- AlphaMissense 0.12
- MetaLR 0.65
- MetaSVM -0.04
- CADD 21.80
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available