P4S (p.Pro4Ser) variant of HOGA1 (Q86XE5)
P4S (p.Pro4Ser) in HOGA1 (Q86XE5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P4S (p.Pro4Ser) variant details
- p.Pro4Ser
- gnomAD rs1379254611
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.14
- ESM-1b 0.00
- AlphaMissense 0.07
- MetaLR 0.58
- MetaSVM -0.28
- CADD 14.04
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available