L61P (p.Leu61Pro) variant of HOGA1 (Q86XE5)
L61P (p.Leu61Pro) in HOGA1 (Q86XE5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
L61P (p.Leu61Pro) variant details
- p.Leu61Pro
- gnomAD 10-97584885-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.773
- REVEL 0.80
- ESM-1b 1.00
- AlphaMissense 0.98
- MetaLR 0.92
- MetaSVM 1.05
- CADD 28.50
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available