L2P (p.Leu2Pro) variant of HOGA1 (Q86XE5)
L2P (p.Leu2Pro) in HOGA1 (Q86XE5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
L2P (p.Leu2Pro) variant details
- p.Leu2Pro
- gnomAD 10-97584708-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.557
- REVEL 0.53
- ESM-1b 0.52
- AlphaMissense 0.08
- MetaLR 0.84
- MetaSVM 0.87
- CADD 25.30
- Population evidence available
- Structural context available
- Literature evidence available