I35T (p.Ile35Thr) variant of HOGA1 (Q86XE5)
I35T (p.Ile35Thr) in HOGA1 (Q86XE5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
I35T (p.Ile35Thr) variant details
- p.Ile35Thr
- gnomAD rs1254351374
- Missense
- Variant Prioritization Score for Impact Estimate 0.617
- REVEL 0.56
- ESM-1b 1.00
- AlphaMissense 0.44
- MetaLR 0.87
- MetaSVM 0.95
- CADD 24.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available