G23E (p.Gly23Glu) variant of HOGA1 (Q86XE5)
G23E (p.Gly23Glu) in HOGA1 (Q86XE5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
G23E (p.Gly23Glu) variant details
- p.Gly23Glu
- gnomAD 10-97584771-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.11
- ESM-1b 0.10
- AlphaMissense 0.10
- MetaLR 0.51
- MetaSVM -0.44
- CADD 11.67
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available