G23A (p.Gly23Ala) variant of HOGA1 (Q86XE5)
G23A (p.Gly23Ala) in HOGA1 (Q86XE5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
G23A (p.Gly23Ala) variant details
- p.Gly23Ala
- gnomAD 10-97584771-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.11
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.52
- MetaSVM -0.47
- CADD 7.09
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available