F69L (p.Phe69Leu) variant of HOGA1 (Q86XE5)
F69L (p.Phe69Leu) in HOGA1 (Q86XE5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
F69L (p.Phe69Leu) variant details
- p.Phe69Leu
- gnomAD 10-97584910-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.50
- ESM-1b 0.00
- AlphaMissense 0.89
- MetaLR 0.50
- MetaSVM -0.62
- CADD 17.67
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available