G137R (p.Gly137Arg) variant of HNRNPU (Q00839)
G137R (p.Gly137Arg) in HNRNPU (Q00839) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G137R (p.Gly137Arg) variant details
- p.Gly137Arg
- ExAC rs771002033
- gnomAD rs771002033
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.04
- ESM-1b 0.14
- AlphaMissense 0.92
- CADD 22.90
- PolyPhen-2 0.03
- SIFT 0.16
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available