S6F (p.Ser6Phe) variant of HNRNPA1 (P09651)
S6F (p.Ser6Phe) in HNRNPA1 (P09651) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
S6F (p.Ser6Phe) variant details
- p.Ser6Phe
- NCI-TCGA Cosmic COSV5293
- NCI-TCGA Cosmic COSV9926
- cosmic curated COSV99267
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.36
- CADD 24.80
- PolyPhen-2 0.29
- SIFT 0.04
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available