V56M (p.Val56Met) variant of HNF4A (P41235)

Name: HNF4A V56M (p.Val56Met) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-20
License: https://catvariant.com/terms-of-use

V56M (p.Val56Met) in HNF4A (P41235) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.

V56M (p.Val56Met) variant details

p.Val56Met
rs2071197
gnomAD 20-44401795-G-A
Missense
Variant Prioritization Score for Impact Estimate 0.0807
CADD 0.01
Most common in the HGDP:SURUI population (allele frequency 1)
Structural context available
Cited in: Association of Hepatic Nuclear Factor 4 Alpha Gene Polymorphisms With Free Imatinib Plasma Levels and Adverse Reactions… (PMID 31045869)
Cited in: Association of STAT-3 rs1053004 and VDR rs11574077 With FOLFIRI-Related Gastrointestinal Toxicity in Metastatic… (PMID 29706892)