V31A (p.Val31Ala) variant of HNF4A (P41235)
V31A (p.Val31Ala) in HNF4A (P41235) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
V31A (p.Val31Ala) variant details
- p.Val31Ala
- ExAC rs752973948
- gnomAD rs752973948
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- REVEL 0.25
- MetaLR 0.56
- MetaSVM -0.84
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available