M10V (p.Met10Val) variant of HNF4A (P41235)
M10V (p.Met10Val) in HNF4A (P41235) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
M10V (p.Met10Val) variant details
- p.Met10Val
- cosmic curated COSV10733
- ExAC rs775567227
- TOPMed rs775567227
- gnomAD rs775567227
- Missense
- Variant Prioritization Score for Impact Estimate 0.76
- REVEL 0.81
- MetaLR 0.84
- MetaSVM 0.85
- CADD 25.30
- PolyPhen-2 0.69
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available