S59G (p.Ser59Gly) variant of HMGCR (P04035)
S59G (p.Ser59Gly) in HMGCR (P04035) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
S59G (p.Ser59Gly) variant details
- p.Ser59Gly
- gnomAD rs1232088692
- Missense
- Variant Prioritization Score for Impact Estimate 0.584
- REVEL 0.58
- CADD 23.20
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available