P28S (p.Pro28Ser) variant of HLA-DQB1 (P01920)
P28S (p.Pro28Ser) in HLA-DQB1 (P01920) is a missense change. Clinical records from EBI and UniProt describe it as benign in the context of in allele DQB1*05:01 and allele DQB1*05:02. The record also includes population frequency data, published literature, and structural context.
P28S (p.Pro28Ser) variant details
- p.Pro28Ser
- rs1049061
- UniProt VAR 062686
- 1000Genomes rs1049061
- ExAC rs1049061
- Benign
- in allele DQB1*05:01 and allele DQB1*05:02
- Missense
- EBI: Benign (in allele DQB1*05:01 and allele DQB1*05:02)
- UniProt: Benign (in allele DQB1*05:01 and allele DQB1*05:02)
- Population evidence available
- Structural context available
- Cited in: Complete sequence of the HLA DQ alpha and DQ beta cDNA from a DR5/DQw3 cell line. (PMID 3584986)