L260R (p.Leu260Arg) variant of HLA-DQB1 (P01920)
L260R (p.Leu260Arg) in HLA-DQB1 (P01920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L260R (p.Leu260Arg) variant details
- p.Leu260Arg
- rs1251210368
- gnomAD 6-32660243-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.13
- CADD 23.40
- PolyPhen-2 0.22
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available