L259P (p.Leu259Pro) variant of HLA-DQB1 (P01920)
L259P (p.Leu259Pro) in HLA-DQB1 (P01920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
L259P (p.Leu259Pro) variant details
- p.Leu259Pro
- rs1387826523
- gnomAD 6-32660246-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.14
- CADD 24.60
- PolyPhen-2 1.00
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available