L259I (p.Leu259Ile) variant of HLA-DQB1 (P01920)
L259I (p.Leu259Ile) in HLA-DQB1 (P01920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
L259I (p.Leu259Ile) variant details
- p.Leu259Ile
- gnomAD 6-32660247-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.11
- CADD 22.40
- PolyPhen-2 1.00
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available