L259F (p.Leu259Phe) variant of HLA-DQB1 (P01920)
L259F (p.Leu259Phe) in HLA-DQB1 (P01920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
L259F (p.Leu259Phe) variant details
- p.Leu259Phe
- rs1782853786
- gnomAD 6-32660247-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.12
- CADD 23.00
- PolyPhen-2 1.00
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available