H261Y (p.His261Tyr) variant of HLA-DQB1 (P01920)
H261Y (p.His261Tyr) in HLA-DQB1 (P01920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
H261Y (p.His261Tyr) variant details
- p.His261Tyr
- rs776366076
- gnomAD 6-32660241-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.12
- CADD 23.80
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available