H261L (p.His261Leu) variant of HLA-DQB1 (P01920)
H261L (p.His261Leu) in HLA-DQB1 (P01920) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
H261L (p.His261Leu) variant details
- p.His261Leu
- gnomAD 6-32660240-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.13
- CADD 21.30
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available