Y51S (p.Tyr51Ser) variant of HLA-C (P10321)
Y51S (p.Tyr51Ser) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
Y51S (p.Tyr51Ser) variant details
- p.Tyr51Ser
- Ensembl rs2113914967
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.20
- CADD 26.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available