Y51D (p.Tyr51Asp) variant of HLA-C (P10321)
Y51D (p.Tyr51Asp) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
Y51D (p.Tyr51Asp) variant details
- p.Tyr51Asp
- gnomAD rs281860346
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.24
- CADD 27.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.1e-05)
- Structural context available