Y31S (p.Tyr31Ser) variant of HLA-C (P10321)
Y31S (p.Tyr31Ser) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
Y31S (p.Tyr31Ser) variant details
- p.Tyr31Ser
- ExAC rs281860326
- gnomAD rs281860326
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.18
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available