Y31F (p.Tyr31Phe) variant of HLA-C (P10321)
Y31F (p.Tyr31Phe) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
Y31F (p.Tyr31Phe) variant details
- p.Tyr31Phe
- ExAC rs281860326
- gnomAD rs281860326
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.12
- CADD 23.80
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available