Y31C (p.Tyr31Cys) variant of HLA-C (P10321)
Y31C (p.Tyr31Cys) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
Y31C (p.Tyr31Cys) variant details
- p.Tyr31Cys
- ExAC rs281860326
- gnomAD rs281860326
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.18
- CADD 24.50
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the East Asian population (allele frequency 3.6e-05)
- Structural context available