V3I (p.Val3Ile) variant of HLA-C (P10321)
V3I (p.Val3Ile) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
V3I (p.Val3Ile) variant details
- p.Val3Ile
- 1000Genomes rs2113916858
- Missense
- Variant Prioritization Score for Impact Estimate 0.115
- REVEL 0.12
- CADD 7.39
- PolyPhen-2 0.22
- SIFT 0.05
- Most common in the 1KG:STU population (allele frequency 0.0068)
- Structural context available