T34I (p.Thr34Ile) variant of HLA-C (P10321)
T34I (p.Thr34Ile) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
T34I (p.Thr34Ile) variant details
- p.Thr34Ile
- 1000Genomes rs281860331
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.17
- CADD 22.20
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the East Asian population (allele frequency 0.00045)
- Structural context available