T34A (p.Thr34Ala) variant of HLA-C (P10321)
T34A (p.Thr34Ala) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
T34A (p.Thr34Ala) variant details
- p.Thr34Ala
- gnomAD rs281860330
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.14
- CADD 22.60
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available