S37Y (p.Ser37Tyr) variant of HLA-C (P10321)
S37Y (p.Ser37Tyr) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S37Y (p.Ser37Tyr) variant details
- p.Ser37Tyr
- ExAC rs281860332
- gnomAD rs281860332
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.19
- CADD 25.80
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 4.3e-06)
- Structural context available