S37C (p.Ser37Cys) variant of HLA-C (P10321)
S37C (p.Ser37Cys) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S37C (p.Ser37Cys) variant details
- p.Ser37Cys
- ExAC rs281860332
- gnomAD rs281860332
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.20
- CADD 26.10
- PolyPhen-2 0.93
- SIFT 0.00
- Population evidence available
- Structural context available