S28Y (p.Ser28Tyr) variant of HLA-C (P10321)
S28Y (p.Ser28Tyr) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
S28Y (p.Ser28Tyr) variant details
- p.Ser28Tyr
- ExAC rs11547360
- gnomAD rs11547360
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.18
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.3e-06)
- Structural context available