S26P (p.Ser26Pro) variant of HLA-C (P10321)
S26P (p.Ser26Pro) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
S26P (p.Ser26Pro) variant details
- p.Ser26Pro
- Ensembl rs41546415
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.16
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 3.3e-06)
- Structural context available