S26F (p.Ser26Phe) variant of HLA-C (P10321)
S26F (p.Ser26Phe) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S26F (p.Ser26Phe) variant details
- p.Ser26Phe
- Ensembl rs281860319
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.15
- CADD 23.90
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.3e-05)
- Structural context available