R7G (p.Arg7Gly) variant of HLA-C (P10321)
R7G (p.Arg7Gly) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R7G (p.Arg7Gly) variant details
- p.Arg7Gly
- gnomAD rs878995294
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.16
- CADD 18.80
- PolyPhen-2 0.66
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 4.2e-06)
- Structural context available