R41S (p.Arg41Ser) variant of HLA-C (P10321)
R41S (p.Arg41Ser) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R41S (p.Arg41Ser) variant details
- p.Arg41Ser
- cosmic curated COSV66110
- 1000Genomes rs41555420
- ExAC rs41555420
- gnomAD rs41555420
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.12
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the 1KG:YRI population (allele frequency 0.029)
- Structural context available