R41L (p.Arg41Leu) variant of HLA-C (P10321)
R41L (p.Arg41Leu) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R41L (p.Arg41Leu) variant details
- p.Arg41Leu
- cosmic curated COSV10532
- ExAC rs41560916
- gnomAD rs41560916
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.18
- CADD 16.30
- PolyPhen-2 1.00
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 2.1e-05)
- Structural context available