R41C (p.Arg41Cys) variant of HLA-C (P10321)
R41C (p.Arg41Cys) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R41C (p.Arg41Cys) variant details
- p.Arg41Cys
- 1000Genomes rs41555420
- ExAC rs41555420
- gnomAD rs41555420
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.10
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available