R38G (p.Arg38Gly) variant of HLA-C (P10321)
R38G (p.Arg38Gly) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
R38G (p.Arg38Gly) variant details
- p.Arg38Gly
- 1000Genomes rs41542423
- ExAC rs41542423
- TOPMed rs41542423
- gnomAD rs41542423
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.18
- CADD 23.30
- PolyPhen-2 0.03
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4e-05)
- Structural context available