R2P (p.Arg2Pro) variant of HLA-C (P10321)
R2P (p.Arg2Pro) in HLA-C (P10321) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
R2P (p.Arg2Pro) variant details
- p.Arg2Pro
- cosmic curated COSV99058
- 1000Genomes rs772484756
- ExAC rs772484756
- gnomAD rs772484756
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.08
- CADD 10.80
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the HGDP:YORUBA population (allele frequency 0.033)
- Structural context available